The Metabolic Health Lab

The Metabolic Health Lab

Seeking evidence in herbal medicine

How to navigate influencers and science papers

Kristen Deuel, MSc's avatar
Kristen Deuel, MSc
Jun 30, 2025
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The concept of ‘hierarchy of evidence’ serves as a rough guide for evaluating research, but is just that: a guide. In the context of herbal medicine, which evolved through observation, tradition, and pattern recognition, applying this model too rigidly could flatten nuance. However, for clinicians and researchers working to bridge science and plant medicine, understanding where different forms of evidence fit and how to interpret them critically is essential.

The hierarchy of research evidence

At the upper end of this hierarchy are meta-analyses and systematic reviews. These studies generate new data by compiling and assessing existing research to uncover new patterns. Their strength lies in their breadth, but the accuracy of their conclusions depends entirely on the quality of the studies they include (Greenhalgh, 2023). One step below are randomized controlled trials (RCTs), which attempt to isolate a single variable – in this case, an herbal intervention – through strict experimental…

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